Migraine Mayhem: The Secrets Behind That Pesky Pain

Written by: Baldomero Garza



Time to read 3 min

Ah, the ever-elusive migraine: a mysterious fiend with a flair for the dramatic. From blinding you with flashing lights to leaving you unable to enjoy wine night, migraines are notorious for crashing the party in the least fun way possible. 


That being said, today, we’re diving deep into the world of migraines, armed with scientific studies, natural remedies, and just a pinch of snark. Buckle up!

The Migraine Mystique: Inflammation & Glutamate

First off, let's start with the basics. You know that throbbing feeling in your head? That's not just you overdramatizing after a long Monday; it's your body's way of saying, "Hey! Something’s up!"(1). 

Migraines are like that nosy neighbor who always knows when you’ve sneaked an extra cookie—or five. They're basically a sign that there's inflammation in the body. And the star of this inflammation show? Glutamate. 

Yes, the very neurotransmitter responsible for transmitting pain and other fun sensations in our brain(2).

Now, let's talk Vitamin B6.


If migraines were a blockbuster movie, Vitamin B6 would be the unsung hero working behind the scenes. Not only does it convert that drama queen glutamate into the chill GABA, but it’s also involved in a slew of other pathways to keep neural excitement in check(3).


Imagine B6 as that one friend who always has a solution for every hiccup during your road trips. Flat tire? No problem! Forgot the snacks? They’ve got a stash!


Speaking of saviors, ever heard of NAC? 


No, it's not the latest hipster coffee order but something potentially more awesome. NAC modulates the glutamatergic system, helping maintain a balance in the force... err... neurotransmitter levels(4)

b6 - msw the awesome vitamins

Unmasking The Culprits: The Migraine Trigger List

Migraines are a bit like those detective stories where everyone is a suspect. From stress to chocolate, various factors could potentially 'trigger' these headaches(1). 


But let’s get real, pointing fingers at chocolate? That's just blasphemy!


But there’s more to this plot twist: did you know your body's internal clock, hormonal changes, and even the aroma of your favorite perfume might play a role in triggering migraines? Yep, even your favorite scents could betray you(1). Talk about drama!

Mother Nature’s Medicine Cabinet

Tired of the headache from  your... well, headache? Let’s stroll through Mother Nature’s pharmacy:

  1. Turmeric & Fish Oil: Not just for delicious curries, turmeric is a potential migraine ally. Pair it with fish oil, and you might just be onto a winner combo.
  2. Vitamin D: Speaking of sunlight and joy, let’s bring in the Vitamin D. Some studies suggest that consistent doses might reduce the frequency of migraine attacks(4). Plus, getting that sunny D (especially in The D, Msw’s special blend with K2) might give you those radiant, “I just had 8 hours of sleep” vibes even if you didn’t.
  3. Melatonin: Not only great for sleep but potentially a champion for pain relief.
VIntage Medicine Cabinet, turmeric, fish oil, msw

A Chiropractic Charm?

Time to crack the case (and maybe your back too, but in a good way!). Several studies hint that chiropractic spinal manipulative therapy might be a solid ally in the fight against migraines(1). So, if you’ve been shrugging off those chiropractor visits, maybe it’s time to give it a shot.

The Dark Plot Twist: Migraines & Strokes

We can't wrap up our migraine tale without addressing the ominous connection to strokes. There's a small but significant link between migraines (especially those with aura) and the risk of strokes(1). This isn’t to scare you, but to remind everyone that it’s essential to stay informed and proactive about our health.

Wrapping Up the Whodunnit

In conclusion, migraines are a complex mystery, but with a bit of knowledge (and perhaps a dash of wit), they can become a tad more manageable. And if you're looking to boost your defenses naturally, don't forget to check out The D, Msw's unique blend of Vitamin D3 with K2. It’s the perfect ally for those wanting to shine bright, migraine-free!


  1. Goadsby, P.J., et al., "Pathophysiology of Migraine." Neuron, 97(3), 2018.
  2. Ferrari, M.D., et al., "Migraine pathophysiology: lessons from mouse models and human genetics." The Lancet Neurology, 14(1), 2015.
  3. Bottiglieri, T., "Homocysteine and folate metabolism in depression." Progress in Neuro-Psychopharmacology & Biological Psychiatry, 29(7), 2005.
  4. Dean, O., et al., "N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action." The Journal of Psychiatry & Neuroscience, 35(2), 2011.
  5. Martin, V.T., & Behbehani, M.M., "Ovarian hormones and migraine headache: understanding mechanisms and pathogenesis." Headache: The Journal of Head and Face Pain, 46(s2), 2006.
  6. Harriott, A.M., & Schwedt, T.J., "Migraine is associated with altered processing of sensory stimuli." Current Pain and Headache Reports, 18(11), 2014.
  7. Aggarwal, B.B., et al., "Curcumin: the Indian solid gold." Advances in Experimental Medicine and Biology, 595, 2007.
  8. Prakash, S., & Mehta, N.C., "Migraine: Is it related to hormonal disturbances or stress?." International Journal of Women's Health, 6, 2014.
  9. Peres, M.F.P., et al., "Melatonin, 3 mg, is effective for migraine prevention." Neurology, 63(4), 2004.
  10. Bryans, R., et al., "Evidence-based guidelines for the chiropractic treatment of adults with headache." Journal of Manipulative and Physiological Therapeutics, 34(5), 2011.
  11. Spector, J.T., et al., "Migraine and migraine aura and risk of incident stroke in the Women's Health Study." Cephalalgia, 30(4), 2010.

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